Why Praeva?
PRAEVA protects treatment outcomes with targeted, microbiome-safe biofilm control. It elevates clinical care, enhances patient experience, and reinforces your practice’s commitment to long-term success.
The Next Generation of Biofilm Control. Clinically integrated.
What is Biofilm?
Biofilm is the leading cause of dental problems, gum inflammation, and the gradual breakdown of enamel and soft tissue around dental work. Its presence can compromise both health and aesthetics—often invisibly and both in people with natural dentition and dental work.
Biofilm is like and invisible enemy - it hard to see without disclosing. This sticky, protective matrix forms when bacteria cluster together, creating a shield that makes them up to 1,000 times more resistant to traditional treatments. Unlike individual bacteria, biofilm creates its own microenvironment where pathogenic species thrive, producing acids that demineralize enamel and toxins that trigger inflammation. The formation begins within minutes through specialized enzymes called GTF that convert dietary sugars into the structural foundation of biofilm—which is why traditional bacteria-killing approaches often fail.
Equiome™: Biotechnology with Purpose
At the core of PRAEVA is Equiome™—a patented active complex developed through enzymatic activation of a single natural oil. This process amplifies the bioavailability of its free fatty acids by over 300 times, enabling precise, uncompetitive inhibition of GTF enzymes—the key drivers of biofilm matrix formation and acid production. Instead of killing bacteria, Equiome™ alters their behavior, preventing adhesion and exopolysaccharide synthesis without disrupting the natural oral microbiome. The result is biologically selective, microbiome-safe protection—ideal for long-term use around orthodontic attachments, implants, restorations, and gingival margins.
Clinical Results Deserve Clinical Continuity
Modern dentistry delivers outstanding results—yet biofilm remains the primary threat to their longevity. Whether managing aligners, implants, esthetic restorations, or periodontal health, treatment success hinges on what happens after the patient leaves the chair. PRAEVA was developed to close this clinical gap. With targeted, microbiome-respecting biofilm control, it helps prevent complications like white spot lesions, peri-implant inflammation, marginal tissue irritation, and aesthetic breakdown—safeguarding your work, case by case.
A Clinical Offering that Makes The Difference
PRAEVA enables clinics to go beyond treatment delivery and offer a structured system that safeguards outcomes with precision and care. Whether integrated into the full Biofilm Control Protocol or prescribed independently, PRAEVA Pro Care Systems provide a clinically validated way to extend expertise beyond the chair—supporting tissue health, microbiome balance, and long-term stability.
This approach elevates the standard of care patients receive and visibly enhances their experience during treatment. For the clinic, it reduces complications, strengthens case acceptance, and reinforces a reputation for excellence. It positions the practice as prevention-focused, biologically informed, and fully aligned with the highest standard of modern dentistry.
Built for Real Practice, Backed by Science
PRAEVA Equiome Balance was developed by a clinician to meet the demands of real-world dentistry—where precision must align with practicality, and outcomes depend on what patients do every day. It integrates seamlessly into clinical workflows, supports adherence without complexity, and elevates the quality of care delivered between visits.
Available in both fluoride and fluoride-free versions, PRAEVA Equiome Balance allows for tailored recommendations without compromise. For practices committed to excellence, predictability, and microbiome-safe care, it offers more than prevention—it delivers a clear standard of differentiation, aligned with the future of modern dentistry.
FAQ
What is Praeva Equiome™ Balance Toothpaste?
Praeva Equiome™ Balance Toothpaste is a next-generation oral care solution designed for precision biofilm control, microbiome protection, and long-term support of natural teeth and various dental treatments like implants, veneers, crowns, and aligners. It helps prevent biofilm buildup and staining while respecting the oral microbiome's balance.
What is the Equiome™ Free Fatty Acid Complex (EFAC)?
The name Equiome™ comes from equilibrium of the microbiome’ and is the patented name for an active complex created through biotechnological activation of natural oils. It contains beneficial free fatty acids at a concentration more than 300 times higher than in the source oil. Free fatty acids have a proven effect of binding to GTF enzymes, which are responsible for synthesizing polysaccharides – a main structural element of biofilm, and acids that lead to enamel loss of minerals and degradation. This occurs without antiseptic action on the oral microbiome, setting it apart from other antimicrobial products on the market.
How does PRAEVA Equiome Balance toothpaste differ from traditional toothpastes?
Unlike conventional toothpastes that rely on harsh antibacterial agents or abrasives, Praeva targets the root mechanism of biofilm formation without disrupting beneficial bacteria. Its core active ingredient, the Equiome™ Free Fatty Acid Complex, modulates the enzymes responsible for biofilm growth, creating an invisible protective barrier. Traditional approaches often destroy all bacteria, potentially leading to dysbiosis (an imbalance of the oral microbiome), while Praeva aims to preserve microbial harmony.
What are the key benefits of using PRAEVA Equiome™ Balance Toothpaste?
Praeva offers several key benefits, including preventing biofilm buildup on teeth and dental work, balancing the oral microbiome, providing an ultra-smooth and polished sensation, being gentle on restorative materials, keeping aligners clear, promoting gum health around implants and restorations, strengthening enamel, reducing sensitivity, providing long-lasting freshness, and helping prevent staining.
Does PRAEVA Equiome™ Balance Тoothpaste contain fluoride?
Yes, Praeva offers two versions: one with 1450 ppm sodium fluoride, suitable for clinical prevention in patients at risk of caries, and a fluoride-free version for those seeking a natural alternative or who have personal or medical preferences. Both formulas provide effective biofilm control and protection, allowing for individual clinical case considerations.
Is there scientific evidence to support Praeva's effectiveness?
Yes. Equiome™ and PRAEVA Equiome Balance Toothpaste have been extensively researched:
- In vitro on biofilm-producing microorganisms from the mutans group, it shows suppression of the biofilm formation.
- In a bioreactor setting, referred to as ‘artificial mouth study’ simulating a real oral environment, its effectiveness has been confirmed in suppressing biofilm formation on human teeth, without decreasing the microbial count in the system.
- Clinical observations have demonstrated cleaner teeth, reduced inflammation, and improved tissue homeostasis.
- Scanning electron microscopy has been used to visualize the difference in biofilm accumulation when using PRAEVA Equiome Balance toothpaste compared to standard toothpaste in aligner-wearers and patients with temporary crowns undergoing prosthetic treatment.
Is PRAEVA Equiome Balance Toothpaste safe for use with dental implants and peri-implant tissue?
Yes, it is even recommended. The free fatty acids in PRAEVA support the gingival barrier function - they have anti-inflammatory, antioxidant, and hydrating effects. Studies also show that some of the free fatty acids also present in Equiome also inhibit the adhesion of key periodontopathogens like Porphyromonas gingivalis. This results in healthier peri-implant tissue and a lower risk of inflammation in the long term, where chlorhexidine or other aggressive antiseptics are not suited for extended use. This is crucial for long-term implant success, as biofilm is the number one reason for implant failure.
Is PRAEVA Equiome Balance toothpaste suitable for orthodontic treatment and aligners?
Absolutely. Praeva does not harm the surface of aligners or attachments. It reduces biofilm on both teeth and aligners, maintaining their aesthetics and freshness throughout treatment. The combination of ingredients in Praeva helps prevent white spot lesions, inflammation, and acid damage, and keeps aligners clear and odor-free.
Is Praeva suitable for patients with sensitive teeth?
Yes. Praeva contains a high percentage of medical-grade nanohydroxyapatite, which fills micro-cracks in enamel, reduces sensitivity, and restores mineral balance. Additionally, it does not contain irritating chemicals, improving tolerability. In clinical observations, 100% of sensitive patients reported relief.
Why doesn't Praeva use chlorhexidine or other antiseptics?
Long-term use of antiseptics leads to dysbiosis, destroying beneficial flora and creating an environment for aggressive bacterial species. Praeva employs a selective biological approach – it regulates rather than destroys. This allows for continuous daily use without risking microbiome disruption.
Can children and teenagers use Praeva, especially those with aligners?
Yes, the both the fluoride and fluoride-free formula are suitable for children over 7 years old, provided they can tolerate the mint flavor. The product is entirely natural, free from SLS, triclosan, and parabens.
What is the RDA (Relative Dentin Abrasivity) of Praeva, and why is it important?
RDA measures the abrasiveness of toothpaste against dentin, but it is not an indicator of how gentle it is on enamel. Praeva uses a very low abrasiveness, compatible with sensitive teeth, composites, veneers, and implant structures. It uses non-aggressive, biocompatible agents, including nanohydroxyapatite, which itself has a remineralizing effect. This low abrasivity ensures it is safe for delicate restoration surfaces and prevents microscopic scratches.
What are the main ingredients in Praeva toothpaste?
Key ingredients include the Equiome™ Free Fatty Acid Complex, medical-grade nanohydroxyapatite (for enamel restoration and sensitivity reduction), polyphosphates (for stain prevention), and a prebiotic system (xylitol, erythritol, inulin) to support beneficial bacteria and maintain breath freshness.
How should I use Praeva Equiome™ Balance Toothpaste?
For adults and children over 7 years of age: Apply a pea-sized amount to a toothbrush and brush thoroughly your teeth and dental restorations for 2 minutes, twice daily. Do not rinse immediately after brushing – spit and leave to act for continued effect.
- For implants and dental restorations: Brush gently around the implant or tooth-supported restoration and gumline, focusing on the collar area.
- For aligner-wearers: Clean both teeth and aligners with the same paste using separate
Does PRAEVA offer products beyond a single tube of toothpaste?
Yes, Praeva offers Pro Care Systems designed for specific needs. These include the Praeva Perio-Implant and Restorative Pro Care System (6 months of care) and the Praeva Aligner Pro Care System (12 months of care). These systems are typically available exclusively through dental clinics.
Why is PRAEVA important for individuals with aesthetic dental restorations (veneers, crowns, bonding)?
Most oral care products are not designed for the materials and margins of aesthetic restorations and can cause scratches, dullness, and compromise their longevity. Praeva is formulated with biomimetic ingredients and is free of abrasives, actively preventing biofilm buildup – the root cause of discoloration, gum inflammation, and long-term degradation – on these delicate surfaces. It also contains polyphosphates to prevent staining and nanohydroxyapatite to enhance enamel appearance and maintain the seamless look between natural teeth and restorations.
How does PRAEVA Equiome™ Balance Toothpaste contribute to overall oral wellness beyond just cleaning?
PRAEVA recognizes that the oral microbiome directly influences gut health and overall immunity. Unlike traditional toothpastes that use harsh chemicals disrupting this delicate balance, Praeva prevents biofilm formation while preserving beneficial bacteria. Its prebiotic system supports beneficial bacteria, and the nanohydroxyapatite actively rebuilds and strengthens enamel. This approach transforms daily oral care into a foundation for long-term oral and systemic health, supporting the body's natural defense systems.
